According to State Police officials, lanes have been closed on I-664 southbound before Pughsville Road, to make room for Nightingale response teams.
A two vehicle accident has been reported with injuries.
NewsChannel 3's Kristen Crowley says the crash involved a tractor trailer that was located on the right shoulder, and a truck hauling a car that was jack knifed blocking two lanes.
Traffic backed up two miles from the crash and all traffic was stopped for over 20 minutes to clear the scene.
Stay with NewsChannel 3 for updates.